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Effect of pine resin and Biopin ointment on T and B cell immunity

A S Simbirtsev1, V G Konusova, G Sh Mchedlidze

  • 1Institute of Extrapure Biological Preparations, St. Petersburg.

We studied the effects of pine resin and Biopin ointment used for the therapy of burns, wounds, purulent and inflammatory diseases on differentiation of T lymphocyte precursors, lymphocyte proliferation in the thymus and spleen, and production of tumor necrosis factor and interleukins 1, 2, and 6 by splenocytes and peripheral blood leukocytes. The wound-healing effect of these preparations is determined by their pronounced immunomodulatory properties.

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