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[Effects of acoustic stimuli on intracellular free calcium isolated cochlear OHC]
Lin Chuang Er Bi Yan Hou Ke Za Zhi = Journal of Clinical Otorhinolaryngology
|January 25, 2003
Abstract
Objective:
To study the effects of acoustic stimuli upon intracellular free calcium concentration ([Ca2+]i) of cochlear outer hair cells (OHCs) isolated from guinea pigs.
Method:
The specimens were stained with fluorescence, and measured by using ACAS 570.
Result:
Acoustic stimuli caused a remarkable increase of [Ca2+]i and the concentration of [Ca2+]i decreased gradually after reaching its peak value. The reponeses can repeat with another stimuli.
Conclusion:
The acoustic stimuli could alter the physiologic characteristics of single OHC.