Related Experiment Video
Updated: Aug 12, 2026
Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
Published on: January 21, 2018
[Influence of anisodamine on guinea pig experimental nasal hypersensitivity]
1Department of Otolaryngology-Head and Neck Surgery, Chinese Japan United Hospital of Jilin University, Changchun 130031.
Objective:
To observe the influence of anisodamine on guinea pig experimental nasal hypersensitivity.
Method:
Experimental animals were divided into normal control group, TDI group, reserpine group and anisodamine group. The scores of symptom of nose and the cytologic changes of nasal mucosa were parameters of observing.
Result:
The nasal symptom of reserpine group was significantly stronger than the TDI group, and the eosinophilia evidently increased (both P < 0.01). The nasal symptom of the anisodamine group reduced and the eosinophilia decreased. It is significantly difference between the TDI group and the reserpine group (both P < 0.01).
Conclusion:
Anisodamine may play a role in therapy of the experimental nasal hypersensitivity with hyperfunction of parasympathetic nerve.
