Related Experiment Videos
[The study of human papillomavirus(HPV) DNA expression in middle-ear carcinomas]
1Department of Otorhinolaryngology, Third Hospital of Beijing University, Beijing 100083.
Lin Chuang Er Bi Yan Hou Ke Za Zhi = Journal of Clinical Otorhinolaryngology
|January 25, 2003
Abstract
Objective:
To study the expressions of human papillomavirus DNA in the middle-ear carcinomas.
Method:
A PCR method using consensus primers for the detection of HPV6,11,16,18 was applied in 5 biopsies of middle-ear carcinomas. Eight biopsies of mucosa in middle-ear and mastoid were concluded as controls.
Result:
It was found that a resulting 80% (4/5) of the middle-ear carcinomas contained high-risk-type HPV DNA, while the 0%(0/8) of the controls.
Conclusion:
The high prevalence of high-risk-type HPV in carcinomas of the middle ear suggests that viral infections may be an important etiologic component in the carcinogenic process.