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[DNA character of the cholesteatoma]
1Department of Otolaryngology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
Abstract
Objective:
To compare the DNA character with in cholesteatoma tissues with that in normal skin.
Method:
DNA content within 25 cholesteatoma tissues and 10 normal postauricular skin was measured with flow cytometry.
Result:
The content of cholesteatoma tissues and postauricular skin specimens are a normal euploid. The cell number during S phase of cholesteatoma (10.9 +/- 2.32)% was higher than that in normal skin(7.31 +/- 2.82)%.
Conclusion:
Although the cholesteatoma has a very high proliferating character, the result suggest it isn' t a malignant tumor.