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Updated: Aug 10, 2026

Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury
Published on: February 23, 2015
[An experimental study about tiny traumatic measurement of the facial nerve fluid pressure]
Objective:
To study endoneurial fluid pressure (EFP) in facial nerve of normal state.
Method:
EFP was recorded by an active, servo-nulling pressure system in 24 normal guinea pigs.
Result:
The results showed that EFP of the facial nerve was 2.87 +/- 0.51 mmHg and 2.70 +/- 0.43 mmHg in the tympanic and mastoid segment respectively. EFP in the tympanic part was similar to that of mastoid segment. In addition, EFP of facial nerve revealed rhythmic fluctuation within limits.
Conclusion:
It was suggested that measurement of facial nerve pressure by a servonulling system should be useful in evaluating the pathogenesis undelying facial palsy.

