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Updated: Aug 1, 2026
Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications
Published on: May 18, 2017
[Histological structure of adult mouse brain in protein-deficient nutrition]
D I Medvedev1, N N Bogolepov, I Z Eremina
1Scientific Research Institute of Gross and Clinical Pathology, Russian University of People's Friendship and Scientific Research Institute of Brain, RAMS, Moscow.
Abstract:
The effect of protein deficient nutrition on histostructure of different regions of brain of mature animals was studied in the experimental model of protein and energy deficiency. Protein deficient nutrition was shown to exert negative influence on structural and functional state of brain neurons which is manifested through increase of dystrophic changes in neurons of all brain regions, accumulation of lipofuscine in neurons and complex of structural changes in synaptic contacts.
