Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vaccine interchangeability.

David P Greenberg1, Sandor Feldman

  • 1Division of Allergy, Immunology and Infectious Diseases, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213-2583, USA.

Clinical Pediatrics
|March 28, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Term Impacts of Invasive Meningococcal Disease on Survivors and Their Caregivers in the United States and Canada.

Infectious diseases and therapy·2025
Same author

Hypotonic-hyporesponsive Episodes After Diphtheria, Tetanus and Acellular Pertussis Vaccination.

The Pediatric infectious disease journal·2021
Same author

Introductory paper: High-dose influenza vaccine.

Vaccine·2021
Same author

Efficacy and effectiveness of high-dose influenza vaccine in older adults by circulating strain and antigenic match: An updated systematic review and meta-analysis.

Vaccine·2021
Same author

Brand-specific rates of pertussis disease among Wisconsin children given 1-4 doses of pertussis Vaccine, 2010-2014.

Vaccine·2020
Same author

Randomized study of immune responses to two Tdap vaccines among adolescents primed with DTaP and comparison with results among adolescents primed with DTwP.

Vaccine·2019
Same journal

Effect of Preferred Language on Pediatric Rapid Response Activation and Subsequent Intensive Care Utilization.

Clinical pediatrics·2026
Same journal

Documented Caregiver Report of Wheezing at Home is Associated With Decreased Length of Pediatric Asthma Hospitalizations.

Clinical pediatrics·2026
Same journal

The Rash That Will Not Go Away.

Clinical pediatrics·2026
Same journal

Virtual Reality Education for Hospitalized Pediatric Patients Improves Intrinsic Motivation: A Prospective, Randomized Crossover Study.

Clinical pediatrics·2026
Same journal

Pediatric Invasive Group A Streptococcus Characteristics Before, During, and After COVID-19.

Clinical pediatrics·2026
Same journal

Lichen Sclerosus: A Common but Often Overlooked Condition in Pediatric Patients.

Clinical pediatrics·2026
See all related articles

Interchangeable vaccines, like some diphtheria-tetanus-acellular pertussis (DTaP) vaccines, can ensure children stay on schedule. This review examines safety and immune response data for mixed-manufacturer vaccine schedules.

Area of Science:

  • Pediatric Vaccinology
  • Immunology
  • Public Health

Background:

  • Childhood immunization schedules require multiple vaccine doses, posing challenges when single manufacturer products are unavailable.
  • Combination vaccines and product availability issues necessitate understanding vaccine interchangeability for timely immunizations.

Purpose of the Study:

  • To review safety and immunogenicity data for childhood immunization regimens using vaccines from different manufacturers.
  • To inform healthcare providers on vaccine interchangeability to prevent missed vaccination opportunities.

Main Methods:

  • Review of existing safety and immunogenicity data for various vaccine products.
  • Analysis of studies examining mixed-manufacturer vaccine series, particularly for diphtheria-tetanus-acellular pertussis (DTaP) vaccines.

Related Experiment Videos

Main Results:

  • Clear interchangeability data exists for some vaccines (e.g., hepatitis B, Haemophilus influenzae type b).
  • Limited data currently supports the interchangeability of some diphtheria-tetanus-acellular pertussis (DTaP) vaccine products when necessary.
  • The article presents available safety and immunogenicity data for mixed-manufacturer regimens.

Conclusions:

  • Understanding vaccine interchangeability is crucial for maintaining timely childhood immunization schedules.
  • Further research and data are needed to establish the interchangeability of certain vaccine types, like DTaP, to ensure vaccine efficacy and safety.