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Updated: Aug 2, 2026
Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
Published on: June 10, 2017
[Clinical analysis of primary head and neck non-Hodgkin's ]
Shuangle Wang1, Yuanshi Jiang, Wanfen Wu
1Department of Otolaryngology, Head and Neck Surgery, Shantou City Central Hospital, Shantou 515031.
Objective:
To research the clinical features of primary head and neck non-Hodgkin's lymphoms (NHL).
Method:
62 patients with primary head and neck NHL were analyzed in the positions of focuses, clinical aspects, diagnosis and treatment.
Result:
Tonsilla palatina(25.8%), cervical lymphonodi (19.4%), nasal cavity and nasal sinuses(12.9%) were the common place of the origin of NHL which had various clinical manifestations. High-grade malignant lymphomas represented 75.8% of these cases whose I E stage and II E stage were 38.7% and 24.2% respectively. The complete response, partial response, and response rate were 75.8%, 14.5%, and 90.3%, respectively. Some patients had been long-term survival without tumor.
Conclusion:
Head and neck NHL is generally high degree malignancy. It often originates from outside lymph node and easily metastasizes to lymph node. Accurate surgical biopsy linking immunohistochemical test will be advantageous to make a definite diagnosis. Combining Chemotherapy and radiotherapy or operation should be put into practice to improve prognosis.
