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An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

Skin metastasis from prostate adenocarcinoma

Nasir Ali1, Saif ur-Rehman, Mutahir Ali

  • 1Department of Radiation Oncology, Shaukat Khanum Memorial Cancer Hospital, MA Johar Town, Lahore. nasiralidr@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|April 11, 2003
PubMed

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Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...