Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Case report: bilateral Cushing's syndrome].

Héla Cheikhrouhou1, Karima Khiari, Lotfi Chérif

  • 1Service de Néphrologie et de Médecine Interne, Unité d'endocrinologie Hôpital Charles Nicolle, Tunis, Tunisie.

La Tunisie Medicale
|July 10, 2003
PubMed
Summary

This case study details a 49-year-old woman with Cushing

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vitamin B12 levels in type 2 diabetic patients on Metformin compared to those never on Metformin: a cross sectional study in Tunisia.

La Tunisie medicale·2024
Same author

Validation of the Aldosteronoma Resolution Score as a Predictive Resolution Score of Hypertension After Unilateral Adrenalectomy for Primary Aldosteronism in a North-African Population.

World journal of surgery·2023
Same author

Predictors of successful outcome after adrenalectomy for unilateral primary aldosteronism.

Frontiers in endocrinology·2023
Same author

Pre- and Post-treatment Serum BAFF Levels and BAFF Gene Polymorphisms in Patients with Graves' Disease.

Endocrine research·2023
Same author

Atypical parathyroid adenoma: A case report.

Clinical case reports·2022
Same author

Synchronous parathyroid carcinoma and papillary thyroid carcinoma.

Clinical case reports·2022

Area of Science:

  • Endocrinology
  • Neurosurgery
  • Radiology

Background:

  • Cushing's syndrome is a complex endocrine disorder characterized by prolonged exposure to high cortisol levels.
  • Pituitary microadenomas are common causes of Cushing's disease, impacting hormone regulation.
  • Adrenal gland imaging is crucial for diagnosing and understanding the extent of adrenal involvement in Cushing's syndrome.

Observation:

  • A 49-year-old woman presented with clinical signs of Cushing's syndrome.
  • Magnetic Resonance Imaging (MRI) revealed a pituitary microadenoma and a partial empty sella.
  • Computed Tomography (CT) scan demonstrated bilateral adrenal hyperplasia with a significant left-sided nodule and a second smaller nodule.

Findings:

  • The combination of pituitary microadenoma and bilateral adrenal hyperplasia with nodules suggests a potential diagnosis of macronodular adrenocortical hyperplasia.
  • This presentation is indicative of long-standing Cushing's disease.
  • Radiological findings correlate with hormonal imbalances characteristic of Cushing's syndrome.

Implications:

  • Findings highlight the importance of comprehensive imaging in diagnosing complex endocrine disorders.
  • Understanding the specific adrenal pathology is critical for tailoring treatment strategies for Cushing's disease.
  • This case underscores the need for careful follow-up to monitor disease progression and treatment efficacy.

Related Experiment Videos