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Updated: Aug 12, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
[Analysis of optical coherence tomography for macular hole closure after surgery]
1Service d'Ophtalmologie-ULB, Hôpital Erasme. paul.demols@euronet.be
Purpose:
The study of early closure of macular hole after surgery is difficult with intraocular gas. Using silicone oil tamponade, which gives easy access to the fundus from the first postoperative day, the optical coherence tomography (OCT) has been used to make a fine analysis of the macula.
Methods:
Our study included 13 eyes with macular hole which have undergone a vitrectomy with silicone oil tamponade. An OCT was performed before the surgery, on the first postoperative day (J1), 1 week (S1) and 1 month (M1) after surgery.
Results:
The hole closure was confirmed with OCT on the first postoperative day in 11/13 cases. One week after surgery, 12 holes were closed. An old larger hole did not close but its borders were flattened and loosed the cystic aspect.
Conclusions:
OCT in macular hole surgery with silicone oil tamponade confirms that in the majority of the cases the hole closes within the first 24 hours. It seems that the hole closure could be speeded by internal limiting membrane peeling.
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