Related Experiment Video
Updated: Aug 15, 2026

Induction and Testing of Hypoxia in Cell Culture
Published on: August 12, 2011
Changes in tissue histology associated with adaptation and acclimation to hypoxia
1Department of Biochemistry, North Carolina State University, Raleigh 27695-7622.
Abstract:
Newborn kittens are adapted to hypoxia by having an oxygen department respiration rate. In part, this is due to the structure of the liver which results in a great reduction of oxygen consumption in this organ in response to hypoxia. Older animals possess an oxygen independent respiration rate which is not lost when they acclimate to hypoxia. Instead, there are histological changes which permit the liver to consume oxygen at the same rate as before by facilitating intracellular oxygen transport.
Related Concept Videos
Hypoxia
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Cellular Adaptation I: Introduction and Atrophy
Cellular Adaptation II: Hypertrophy
Cellular Adaptation III: Hyperplasia
Cellular Adaptation IV: Dysplasia and Metaplasia

