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DNA binding of a basic leucine-zipper protein with novel folding domain

S Sato1, K Makino, T Morii

  • 1Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan.

Nucleic Acids Symposium Series
|August 9, 2003
PubMed
Summary

Researchers designed a novel DNA-binding motif using structure-based design. This motif mimics the yeast GCN4 protein, binding DNA sequences as a dimer with high affinity and specificity.

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