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Updated: Sep 18, 2026

A Simple Method for Automated Solid Phase Extraction of Water Samples for Immunological Analysis of Small Pollutants
Published on: January 1, 2016
Improving sensitivity by large-volume sample stacking using the electroosmotic flow pump to analyze some nonsteroidal
Alba Macià1, Francesc Borrull, Carme Aguilar
1Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, Plaça Imperial Tàrraco 1, E-43005 Tarragona, Spain.
Abstract:
Large-volume sample stacking using the electroosmotic flow (EOF) pump (LVSEP) has been used to analyze some nonsteroidal anti-inflammatory drugs (NSAIDs) in water samples. With methanol as the run buffer solvent to suppress the EOF, sensitivity was enhanced by 80-100-fold. The sample for the analysis of real water sample was pretreated by solid-phase extraction (SPE). When the method was based on off-line SPE-LVSEP-CE, sensitivity improved by as much as 1000 times.
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