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Cholesterol in normal and pathological seminal plasma
J Valsa1, K P Skandhan, V Umarvanshi
1Department of Physiology, MP Shah Medical College, Jamnagar, India.
Panminerva Medica
|October 1, 1992
Summary
Cholesterol levels in seminal plasma did not differ significantly across various sperm count groups. However, correlations between cholesterol and sperm count varied between normozoospermia and oligozoospermia.
Area of Science:
- Reproductive Biology
- Clinical Chemistry
Background:
- Seminal plasma cholesterol is a key metabolic component.
- Its role in male fertility requires further elucidation.
Purpose of the Study:
- To investigate seminal plasma cholesterol levels in relation to sperm parameters.
- To explore correlations between cholesterol, sperm count, and motility.
Main Methods:
- Analysis of 128 seminal plasma samples from normozoospermia, oligozoospermia, oligoasthenozoospermia, and azoospermia groups.
- Measurement of cholesterol levels and correlation analysis with total spermatozoa count and motility.
Main Results:
- No significant differences in seminal plasma cholesterol levels were observed among the studied groups.
- A positive correlation between cholesterol and sperm count was found in normozoospermia (r=0.35).
- A negative correlation was observed in oligozoospermia (r=-0.04).
- No correlation was found between cholesterol and sperm motility in any group.
Conclusions:
- Seminal plasma cholesterol levels are consistent across different sperm count categories.
- Cholesterol exhibits varying correlations with sperm count depending on fertility status.
- Cholesterol does not appear to correlate with sperm motility.