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Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Published on: July 11, 2013

Pityriasis versicolor.

Aditya K Gupta1, Roma Batra, Robyn Bluhm

  • 1Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Science Center (Sunnybrook Site), University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. agupta@execulink.com

Dermatologic Clinics
|September 6, 2003
PubMed
Summary
This summary is machine-generated.

Pityriasis versicolor is a common fungal infection causing skin discoloration. Antifungal treatments are effective but recurrence is possible in some patients.

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Area of Science:

  • Dermatology
  • Mycology

Background:

  • Pityriasis versicolor is a mild, chronic skin condition.
  • It presents as scaly, discolored lesions on the trunk, influenced by climate.
  • Adolescence is a common onset period due to increased sebaceous gland activity.

Purpose of the Study:

  • To review the pathogenesis and treatment of pityriasis versicolor.
  • To highlight the role of Malassezia yeasts in disease development.
  • To discuss the efficacy and recurrence patterns of antifungal treatments.

Main Methods:

  • Literature review of pityriasis versicolor.
  • Analysis of the role of Malassezia yeast in pathogenesis.
  • Evaluation of antifungal treatment outcomes.

Main Results:

  • Malassezia yeasts, particularly their mycelial form, are implicated in pityriasis versicolor lesions.
  • Antifungal preparations demonstrate effectiveness in treating initial presentations.
  • A proportion of patients experience disease recurrence despite initial treatment.

Conclusions:

  • Pityriasis versicolor is effectively managed with antifungals, but recurrence necessitates ongoing awareness.
  • The pathogenesis involves Malassezia yeast, with lesion appearance varying by climate.
  • Available antifungal formulations are safe and widely used.