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Modulation of Ca2+ release and Na+ channel function in skeletal muscle by fatty acids
J E Fletcher1, S J Wieland, J Beech
1Hahnemann University, Philadelphia, PA.
Advances in Experimental Medicine and Biology
|January 1, 1992
Abstract:
Ca(2+)- and halothane-induced Ca(2+) release and Na+ currents are modulated by free fatty acids (FAs). FA modulation of ion currents may have important implications for general muscle physiology and skeletal muscle disorders, including malignant hyperthermia (MH).