Related Experiment Videos
Effects of diaphragmatic fatigue on phosphoinositide hydrolysis
W M Anderson1, J H Zavecz, P Tso
1Department of Medicine, Veterans Affairs Medical Center, Shreveport, LA.
Advances in Experimental Medicine and Biology
|January 1, 1992
Abstract:
We evaluated the effects of diaphragmatic fatigue on muscle phosphatidylinositol phosphate (PIP) metabolism. Results revealed that the total PIP pool was 76% greater in fatigued rat diaphragms compared to controls, which suggests that fatigue was associated with inhibition of sarcolemmal membrane bound PIP hydrolysis.