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A Comprehensive Pipeline to Assess the Efficiency of Human Erythropoiesis In Vitro and Ex Vivo
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A Comprehensive Pipeline to Assess the Efficiency of Human Erythropoiesis In Vitro and Ex Vivo

Published on: January 10, 2025

Iron particles in normal erythroblasts and normal and pathological erythrocytes

M C BESSIS, J BRETON-GORIUS

    The Journal of Biophysical and Biochemical Cytology
    |May 25, 1957
    PubMed

    Iron-containing granules (40 to 100 A in diameter), in groups or isolated, are present in normal erythroblasts, normoblasts, reticulocytes, and certain pathological erythrocytes. Similar granules are present in macrophages and have been noted in the stroma of erythrocytes following phagocytosis and hemolysis by macrophages. Incorporation of the granules from the macrophage into erythroblasts is presented as a process similar to pinocytosis. The presence of the iron-containing granules within the erythroid cells parallels hemoglobin synthesis.

    Keywords:
    ERYTHROCYTESIRON/in bloodMICROSCOPY, ELECTRON

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