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Ginkgo biloba
Victor S Sierpina1, Bernd Wollschlaeger, Mark Blumenthal
1Dept. Family Medicine, University of Texas Medical Branch, Galveston, Texas 77555-1123, USA. vssierpi@utmb.edu
American Family Physician
|September 19, 2003
Summary
Ginkgo biloba may improve dementia symptoms and is used for conditions like Alzheimer's disease. However, it can increase bleeding risk when combined with certain medications.
Area of Science:
- Herbal medicine
- Pharmacology
- Neurology
Background:
- Ginkgo biloba is frequently used for Alzheimer's disease, vascular dementia, peripheral claudication, and tinnitus.
- Previous research has explored ginkgo's effectiveness in cerebrovascular diseases and dementia.
Purpose of the Study:
- To review the clinical efficacy, safety, dosing, and pharmacology of Ginkgo biloba.
- To evaluate the use of ginkgo in managing dementia and related conditions.
Main Methods:
- Systematic review of multiple clinical trials.
- Analysis of existing literature on Ginkgo biloba efficacy and safety.
Main Results:
- Systematic reviews indicate Ginkgo biloba may improve dementia symptoms.
- Ginkgo biloba is generally well-tolerated.
- Potential increased bleeding risk when co-administered with anticoagulants, antiplatelet agents, and certain herbs.
Conclusions:
- Ginkgo biloba shows potential for improving dementia symptoms.
- Clinical considerations include safety, appropriate dosing, perioperative use, and drug interactions.
- Further research may clarify optimal use and management of potential risks.