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[Clinical application of phase contrast angiography].
H Matsuzawa1, K Houkin, M Nomura
1Department of Neurosurgery, Hokkaido University School of Medicine.
No Shinkei Geka. Neurological Surgery
|October 1, 1992
Summary
Phase contrast angiography offers non-invasive visualization of cerebral and spinal vascular diseases, providing both anatomical and functional blood flow images. This technique aids in diagnosing conditions like occlusive disease, moyamoya disease, arteriovenous malformations, and aneurysms.
Area of Science:
- Medical Imaging
- Neurology
- Cardiovascular Science
Background:
- Magnetic Resonance Angiography (MRA) traditionally requires contrast medium injection.
- Non-invasive imaging techniques are crucial for evaluating complex vascular conditions.
Purpose of the Study:
- To evaluate the efficacy of Phase Contrast Angiography (PCA) for diagnosing cerebral and spinal vascular diseases.
- To assess PCA's ability to visualize vascular anatomy and blood flow dynamics non-invasively.
Main Methods:
- Utilized a General Electric SIGNA 1.5 tesla NMR scanner.
- Scanned 191 patients with various cerebral and spinal vascular diseases using PCA.
- Employed flow encoding gradient pulses to differentiate moving spins from stationary tissue.
Main Results:
- PCA successfully visualized occlusions, aneurysms, bypassed vessels, and arteriovenous malformations.
- Compared to conventional angiography for stenotic findings, PCA had a 39.1% false positive ratio.
- PCA provided both anatomical and functional (blood flow pattern) imaging.
Conclusions:
- Phase contrast angiography is a valuable non-invasive tool for diagnosing cerebral and spinal vascular diseases.
- PCA offers clinically relevant insights into vascular hydrodynamics.
- The technique provides both anatomical and functional information, enhancing diagnostic capabilities.