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Meningitis due to Prototheca wickerhamii in a patient with AIDS
Z C Kaminski1, R Kapila, L R Sharer
1Department of Laboratory Medicine, UMDNJ-New Jersey Medical School, University Hospital, Newark 07103-2425.
Abstract:
The first documented case of algal meningitis due to Prototheca wickerhamii is reported in a patient with AIDS. The initial CSF culture yielded only Cryptococcus neoformans. P. wickerhamii was isolated on four subsequent lumbar punctures. The patient died, and at autopsy the alga was isolated from leptomeninges over the brain and about the spinal cord. Histologic sections from numerous locations of the brain revealed masses of cryptococci and prototheca.