Related Experiment Video
Updated: Aug 30, 2026

Lipid Bilayer Experiments with Contact Bubble Bilayers for Patch-Clampers
Published on: January 16, 2019
Interaction of K7Fe3+P2W17O62H2 with supported bilayer lipid membranes on platinum electrode
Jianguo Wang1, Li Wang, Shaoqin Liu
1State Kay Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China.
Abstract:
The influence of K(7)Fe(3+)P(2)W(17)O(62)H(2) on l-alpha-phosphatidylcholine/cholesterol bilayer lipid membrane on Pt electrode was studied by voltammetry and AC impedance spectroscopy. The interaction of the polyoxometalates with the BLM can promote the access of Ru(NH(3))(6)(3+) and [Fe(CN)(6)](3-/4-) to the electrode surface. It was found that some kind of pores had been formed on the BLM by AFM. The phenomenon is attributed to the interaction of K(7)Fe(3+)P(2)W(17)O(62)H(2) with phosphatidylcholine phosphate groups located in its outer leaflet. Experimental results are helpful to understand the biological activity of the polyoxometalates in vivo.
Related Concept Videos
Asymmetric Lipid Bilayer
Potentiometry: Membrane Electrodes

