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Resolution of fish allergy: a case report
1The Corvallis Clinic, Corvallis, Oregon 97330, USA. roland.solensky@corvallis-clinic.com
Summary
Fish allergy, often considered lifelong, can resolve in adults. A 68-year-old man with a history of fish hypersensitivity experienced resolution of his IgE-mediated fish allergy.
Area of Science:
- Allergy and Immunology
- Clinical Medicine
Background:
- Fish allergy is a prevalent and typically lifelong food hypersensitivity.
- Previous literature lacks reports on the resolution of fish allergy.
Observation:
- A 68-year-old male with a documented history of fish-induced anaphylaxis.
- Underwent repeat prick-puncture skin testing and an open food challenge with halibut.
Findings:
- Initial skin tests indicated strong positive reactions to multiple fish species.
- Subsequent testing in 2002 yielded negative results for several fish species.
- The patient successfully tolerated a halibut challenge and regularly consumed fish without reactions for 8 months.
Implications:
- This case challenges the notion that fish allergy is invariably lifelong.
- Suggests the need for reevaluation of allergy status in adults with a history of fish hypersensitivity.
- Highlights potential for resolution and improved quality of life.