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An efficient recognition motif for an alkyl moiety in water
Tadashi Mizutani1, Katsuyuki Kozake, Kenji Wada
1Department of Molecular Science and Technology, Faculty of Engineering, Doshisha University, Kyotanabe, Kyoto 610-0321, Japan. tmizutan@mail.doshisha.ac.jp
Abstract:
The artificial receptor bearing decamethylene groups bridging the porphyrin framework and the hydrophilic poly(ethylene oxide) auxiliary groups showed incremental binding free energy of 3.5 kJ mol(-1) per CH2 for 4-alkylpyridines, demonstrating that an ideal hydrophobic environment for the recognition of an alkyl group is constructed in water.
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