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Updated: Aug 14, 2026

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
Published on: June 1, 2011
Carbon and gold electrodes as electrochemical transducers for DNA hybridisation sensors
Fausto Lucarelli1, Giovanna Marrazza, Anthony P F Turner
1Dipartimento di Chimica, Universita' degli Studi di Firenze, via della Lastruccia 3, 50019 Sesto Fiorentino, Firenze, Italy. fausto.lucarelli@unifi.it
Abstract:
Genosensor technology relying on the use of carbon and gold electrodes is reviewed. The key steps of each analytical procedure, namely DNA-probe immobilisation, hybridisation, labelling and electrochemical investigation of the surface, are discussed in detail with separate sections devoted to label-free and newly emerging magnetic assays. Special emphasis has been given to protocols that have been used with real DNA samples.

