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Updated: Aug 18, 2026

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology
Published on: May 18, 2022
[Giant cell tumor of temporal bone: a report of 7 cases]
1Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022.
Objective:
To investigate the clinical course, auxiliary examinations, histologic feature, diagnosis, differential diagnosis and treatment of giant cell tumor of temporal bone (GCTTB).
Method:
Seven cases of GCTTB, which arose in temporal bone, were collected from 1990 to 2002 and analyzed clinicopathologically.
Result:
Seven cases with the GCTTB are reported, including 3 females, 4 males. The age of 7 patients between 9 to 53 years. Five tumors located in right side temporal bone, two in left side temporal bone. One patients was pathological I grade, two I-II grade, and four II grade. The clinical course were different according to the position of the tumors: including tinnitus 6 cases, tinnitus with hear loss 5 cases(2 cases with anakus of trouble side ear), vertigo 1 case, facial paralysis with hear loss 1 case. Radical resections were performed in five cases and subtotal resections in two (recurrence, one year after operation, II grade pathologically). Postoperative Radiotherapy was conducted in three cases.
Conclusion:
Diagnosis of GCTTB is based on typical histologic features and imagine as well as clinical information. Complete surgical resection is believed to be the most suitable treatment for GCTTB and postoperative radiotherapy may be effective.

