Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Neuroleukemia in suckling mice].

S A Petrov

    Gematologiia I Transfuziologiia
    |May 1, 1992
    PubMed
    Summary
    This summary is machine-generated.

    In suckling mice with leukemia, vertebral canal lesions were common due to leukemic infiltrates damaging developing bone. This bone immaturity may accelerate neuroleukemia development.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A series of conjugates based on prostate-specific membrane antigen ligands with the chelating agent DOTA: synthesis, radiolabeling, and biological activity.

    European journal of medicinal chemistry·2025
    Same author

    [Neuroprotective therapy of glaucoma].

    Vestnik oftalmologii·2025
    Same author

    [Neuroprotective therapy for age-related macular degeneration].

    Vestnik oftalmologii·2024
    Same author

    The Influence of Metabolites of Microorganisms of the Genus Bacillus from Permafrost Rocks on T Lymphocyte Differentiation.

    Bulletin of experimental biology and medicine·2024
    Same author

    [The role of mitochondrial dysfunction in the stabilization of the glaucomatous process].

    Vestnik oftalmologii·2024
    Same author

    The Influence of Permafrost Microorganisms on Monocytes Differentiation In Vitro.

    Bulletin of experimental biology and medicine·2023

    Area of Science:

    • Histopathology
    • Oncology
    • Pediatric Pathology

    Context:

    • Study examines 55 suckling mice, both intact and with transplantable leukemia.
    • Focuses on histological analysis of the entire skull and spinal column.

    Purpose:

    • To investigate the pathological changes in the vertebral canal of young mice with leukemia.
    • To understand the relationship between bone development and neuroleukemia progression.

    Summary:

    • Leukemic infiltrates extensively invaded vertebral bodies with incomplete cortical bone formation.
    • Lesions predominantly affected the vertebral canal, indicating a pathway for neuroleukemia spread.
    • Incomplete bone marrow tissue formation in young mice appears to facilitate rapid neuroleukemia development.

    Related Experiment Videos

    Impact:

    • Highlights the vulnerability of immature bone tissue to leukemic infiltration.
    • Suggests a mechanism for the rapid onset of neuroleukemia in young mammals.
    • Provides insights into age-dependent factors influencing cancer metastasis in bone.