Related Experiment Videos
Generation of mutant mice lacking surface expression of CD4 or CD8 gene targeting
T W Mak1, A Rahemtulla, M Schilham
1Ontario Cancer Institute, Department of Medical Biophysics, University of Toronto, Toronto, Canada.
Advances in Experimental Medicine and Biology
|January 1, 1992
Abstract:
With the use of homologous recombination in embryonic stem cells, two new strains of mice lacking surface CD4 or CD8 expression have been generated. It is hoped that they will be useful mouse strains for the study of autoimmune diseases, tissue transplantation rejections and tumour rejections.