Related Experiment Videos
Abnormal spinal curvature in the fetus
L A Harrison1, D H Pretorius, N E Budorick
1Department of Diagnostic Radiology, University of Kansas Medical Center, Kansas City 66160.
Summary
Abnormal fetal spinal curvature, even when mild, is a significant prenatal finding. Early detection via sonography aids in managing associated anomalies and improving infant outcomes.
Area of Science:
- Medical Imaging
- Prenatal Diagnosis
- Fetal Medicine
Background:
- Abnormal fetal spinal curvature is a complex condition.
- Sonographic detection plays a crucial role in prenatal assessment.
Purpose of the Study:
- To determine the clinical significance of sonographically detected fetal spinal curvature.
- To evaluate outcomes associated with fetal spinal abnormalities.
Main Methods:
- Retrospective review of 20 cases with sonographically detected abnormal fetal spinal curvature.
- Analysis of associated anomalies and infant survival rates.
Main Results:
- Nineteen of 20 fetuses had associated anomalies, including neural tube and ventral wall defects.
- Only three infants survived, highlighting poor outcomes.
- Isolated scoliosis in one neurologically normal infant with hemivertebrae was noted.
Conclusions:
- Sonographically detected fetal spinal curvature, mild or severe, is a significant finding.
- Prenatal detection is crucial for identifying associated anomalies and guiding postnatal management, even in isolated cases.
Related Concept Videos
Neurulation
45.2K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
45.2K
Spinal Cord: Gross Anatomy
5.3K
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
5.3K
Vertebral Column: Regions and Curvature
5.9K
The vertebral column or spine is a flexible column that supports the head, neck, and body and allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
5.9K
Fetal Circulation
2.5K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
2.5K
Teratogenicity
3.9K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.9K
General Structure of a Vertebra
6.0K
A typical vertebra, with the exception of the sacrum and coccyx, consists of a body, a vertebral arch, and seven different projections termed processes. The anterior portion of the vertebrae, the body, supports about half the body’s weight. The vertebral bodies progressively increase in size and thickness from the cervical region to the lumbar region of the vertebral column. The intervertebral discs present between the bodies of adjacent vertebrae firmly unites them, forming a continuous...
6.0K