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Updated: Aug 26, 2026

Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery
Published on: September 12, 2015
Glyprolines and semax prevent stress-induced microcirculatory disturbances in the mesentery
G N Kopylova1, E A Smirnova, L Ts Sanzhieva
1Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Russia.
Abstract:
One-hour immobilization stress considerably disturbed microcirculation in the mesentery: blood flow in small mesenteric vessels decreased or stopped and numerous hemorrhages appeared. Lymphatic vessels lost spontaneous activity and did not respond to norepinephrine. Administration of Semax and glyprolines 1 h before stress decreased the severity of stress-induced microcirculatory disturbances. PGP and GP were most effective in this respect.
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