Search research articles

Search research articles

Related Experiment Videos

Controlled functionalization of gold nanoparticles through a solid phase synthesis approach.

James G Worden¹, Andrew W Shaffer, Qun Huo

¹Department of Polymers and Coatings, 1735 NDSU Research Park Drive, Fargo, ND, USA.

Chemical Communications (Cambridge, England)

|February 20, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sepsis After Elective Aortic Root Replacement: An Analysis Using the National Inpatient Sample.

The Journal of surgical research·2026

Same author

Syphilitic Aortitis Presenting With De-Novo Aortic Thrombus and Acute Myocardial Infarction.

JACC. Case reports·2025

Same author

Evaluating a Rapid Immunity Test to Predict Dairy Calf Mortality Risk.

Biology·2025

Same author

Rapid Isolation and Characterization of Exosomes through a Single-Step, Label-Free Protein Biomarker Analysis.

ACS applied bio materials·2025

Same author

Home sleep apnea testing in patients with continuous flow left ventricular assist device: is it feasible?

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine·2025

Same author

Associations of Frailty, Concerns About Falling, and Fall Risk in Community-Dwelling Older Adults in Orlando, Florida: A Preliminary Analysis.

Journal of frailty, sarcopenia and falls·2025

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Researchers developed a new solid phase synthesis method for precisely modifying gold nanoparticles. This strategy enables controlled functionalization, advancing nanoparticle applications.

Area of Science:

Nanotechnology
Materials Science
Synthetic Chemistry

Background:

Gold nanoparticles (AuNPs) are crucial in various fields due to their unique optical and electronic properties.
Controlled functionalization of AuNPs is essential for tailoring their performance in applications like drug delivery and sensing.
Existing methods for AuNP functionalization often face challenges in precision and scalability.

Purpose of the Study:

To develop a novel solid phase synthetic strategy for the controlled functionalization of gold nanoparticles.
To establish a robust and scalable method for precise surface modification of AuNPs.
To demonstrate the versatility of the developed strategy for various functionalization purposes.

Main Methods:

A solid phase synthesis approach was designed and implemented.

Related Experiment Videos

Gold nanoparticles were synthesized and immobilized on a solid support.

Controlled chemical reactions were performed on the immobilized AuNPs to introduce specific functional groups.

Characterization techniques were employed to confirm successful functionalization.

Main Results:

A novel solid phase synthetic strategy for gold nanoparticle functionalization was successfully developed.
The method allows for precise and controlled introduction of functional groups onto the AuNP surface.
The strategy proved to be robust and reproducible, indicating potential for scalability.
Demonstrated successful functionalization with different moieties, highlighting versatility.

Conclusions:

The developed solid phase synthetic strategy offers a significant advancement in the controlled functionalization of gold nanoparticles.
This method provides a reliable platform for creating tailored AuNPs for diverse scientific and technological applications.
The approach paves the way for more sophisticated nanoparticle-based systems and devices.