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Updated: Aug 11, 2026

Evaluating the Function of the Foot Core System in the Elderly
Published on: March 11, 2022
[Osteopathy in diabetic foot syndrome]
I I Dedov1, P V Iushkov, A Iu Tokmakova
1Endocrinological Research Centre, 117036, Moscow.
Abstract:
Morphological characteristics of bone tissues were studied in the feet of patients with diabetes mellitus type 1 and 2 (DM1 and DM2). Osteoblasts and osteoclasts prevalence, the presence of collagen type III in the composition of newly formed bone were characteristic for DM1. Osteocytes prevalence and abundant granulation tissue in newly formed bone was a feature of DM2. The analysis of bone tissue resorption suggests that lacunar osteoclastic resorpsion is the main type in DM1 while periosteocytic osteolysis and smooth resorption are typical for DM2. Thus, osteolysis genesis and synthesis of bone tissue in DM1 and DM2 may be different.
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