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Updated: Aug 25, 2026

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Published on: February 27, 2026
Sarcoma metastatic to the right ventricle: surgical intervention followed by prolonged survival
Matthew T Harting1, Gregory N Messner, Igor D Gregoric
1The Department of Cardiopulmonary Transplantation, Texas Heart Institute, St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
Abstract:
Malignant tumors that metastasize to the heart pose a formidable therapeutic challenge. Recent advances in surgical treatment have improved the management and prognosis of patients with cardiac metastases. We report the case of a 45-year-old man who had a high-grade pleomorphic sarcoma of the right ventricle. We completely resected the neoplasm, reconstructed the right ventricle, and replaced the mitral valve. Upon late follow-up, 67 months (5.6 years) later, the patient was alive and well. This case shows that aggressive surgical management of malignant disease metastatic to the heart can enable prolonged survival.