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An overview of some recent developments in ionization methods for mass spectrometry
1Organic and Biological Mass Spectrometry Group, Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6131, USA. vanberkelgj@ornl.gov
European Journal of Mass Spectrometry (Chichester, England)
|April 22, 2004
Summary
This overview highlights recent advances in mass spectrometry ionization sources since 2000, focusing on techniques for organic and biological analysis. Key methods discussed include electron ionization, chemical ionization, and atmospheric plasma sources.
Area of Science:
- Analytical Chemistry
- Spectrometry
Background:
- Mass spectrometry is a powerful analytical technique.
- Advancements in ionization sources are crucial for expanding its applicability.
Purpose of the Study:
- To provide an overview of recent advances in mass spectrometry ionization sources.
- To focus on techniques relevant to organic and biological analysis published since 2000.
Main Methods:
- Literature review of ionization techniques.
- Author-subjective selection of highlights.
Main Results:
- Coverage of electron ionization and chemical ionization.
- Inclusion of atmospheric plasma, laser desorption, sonic spray, and electrospray ionization sources.
Conclusions:
- Recent developments have expanded the range of ionization sources available for mass spectrometry.
- These advancements are particularly beneficial for organic and biological sample analysis.