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Updated: Aug 24, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Clinical manifestation of aldosteronoma
Maha Al Fehaily1, Quan-Yang Duh
1Department of Surgery, University of Toronto, 100 College Street, Toronto, ON, M5G 1L5, Canada.
Abstract:
Formerly, fewer than 1% of patients with hypertension were believed to have primary hyperaldosteronism; however, recent studies have suggested a higher prevalence, in 5% to 10% of patients with hypertension. Hypokalemia is not necessary for the diagnosis and is probably a sign of more advanced disease. The best diagnostic test is the plasma aldosterone concentration to plasma renin activity (PAC/PRA) ratio. Excess aldosterone level has a deleterious effect on the cardiovascular system. Aldosteronomas should be differentiated from idiopathic hyperaldosteronism (IHA),because they are curable by laparoscopic adrenalectomy.
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