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Embryogenesis of the peripheral nervous system
Ruby J Lien1, Thomas P Naidich, Bradley N Delman
1Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY, USA.
Neuroimaging Clinics of North America
|June 5, 2004
Summary
This review clarifies fetal nervous system development by detailing peripheral nervous system anatomy and embryogenesis terminology. It explores neural development, gross morphology, and molecular signals during maturation.
Area of Science:
- Developmental Biology
- Neuroscience
- Embryology
Background:
- Embryogenesis involves complex, simultaneous, and sequential processes.
- Molecular signals in body patterning are multifunctional and reiterative.
- Understanding neural development requires a clear anatomic model and terminology.
Purpose of the Study:
- To present an anatomic model of the peripheral nervous system.
- To review essential terminology for describing embryogenesis.
- To detail the maturation of the fetal nervous system.
Main Methods:
- Review of existing literature on neural development.
- Description of the evolving gross morphology of the fetal nervous system.
- Analysis of molecular signals involved in developmental patterning.
Main Results:
- A foundational anatomic model for the peripheral nervous system is established.
- Key terminology for embryogenesis is defined.
- Neural development is presented in the context of fetal maturation.
Conclusions:
- A structured approach to understanding embryogenesis is crucial.
- The interplay of gross morphology and molecular signals shapes fetal nervous system development.
- This review provides a framework for studying neural maturation.