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Updated: Aug 24, 2026

Purification of HLA-G+ Extravillous Trophoblasts from Human Term Placental Tissues for Phenotyping and Functional Analysis
Published on: March 13, 2026
[Hemostasis and trophoblast-specific beta 1-glycoprotein in spontaneous abortion]
R N Bogdanovich1, I V Chikalovets, T A Berestovaia
1Far Eeastern Institute of Bioorganic Chemistry, Hospital DVO, RAN, Kirova, 95, Vladivostok, 690022 Russia.
Abstract:
The relationship between the increase in maternal serum concentration of pregnancy-specific beta 1-glycoprotein (SP1) and levels of components of hemostasis system was investigated. The concentrations of SP1 were measured in the blood sera of 234 pregnant women with recurrent spontaneous abortions, in 115 somatically healthy pregnant women and 75 donors. A direct correlation between serum SP1 and levels of components of hemostasis system was shown. Results suggest that disturbances in hemostasis system influence synthesis of some placental proteins, including SP1.
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