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Published on: October 29, 2014
Intensive care needs of children with acute bacterial meningitis: a developing country perspective
Sunit C Singhi1, Rajan Khetarpal, Arun K Baranwal
1Advanced Paediatrics Centre, Department of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh 160-012, India. drsinghi@glide.net.in
Insights
Prioritize children with acute bacterial meningitis (ABM) for paediatric intensive care (PIC) if they show severe symptoms like coma or respiratory distress. Early intervention in PICU is crucial for better outcomes in critically ill children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Critical Care Medicine
Background:
- Paediatric intensive care (PIC) facilities are scarce in developing nations.
- Effective resource allocation requires identifying children who would benefit most from PIC.
Purpose of the Study:
- To identify clinical indicators for intensive care in children with acute bacterial meningitis (ABM).
- To guide prioritization for PIC admission in resource-limited settings.
Main Methods:
- Retrospective, descriptive analysis of 220 children (1 month–12 years) with ABM.
- Data collected from July 1993 to December 1996 at a tertiary-care hospital in India.
- Analysis focused on clinical indicators, interventions, and outcomes in children admitted to or considered for PICU.
Main Results:
- 88 children were transferred to the PICU.
- Common indicators for PICU transfer included coma (Glasgow Coma Score <8, 59%), raised intracranial pressure (44%), shock (24%), and respiratory distress/failure (42%).
- Refractory seizures, need for intubation/ventilation, and multiple system involvement were associated with higher mortality; no deaths occurred in children not transferred to PICU.
Conclusions:
- Children with ABM presenting with Glasgow Coma Score <8, signs of raised ICP, refractory status epilepticus, shock, or respiratory compromise should be prioritized for PIC.
- Timely PICU admission and intervention are critical for improving survival rates in severe ABM cases.
Abstract:
In view of very limited availability of paediatric intensive care (PIC) facilities in developing countries, it is important to define priorities and recognise children who might benefit most from PIC. The objective of this retrospective, descriptive analysis was to identify the clinical indicators for intensive care in children with acute bacterial meningitis (ABM). The study included 220 children aged between 1 month and 12 years with ABM admitted to the paediatric services of an urban, tertiary-care, teaching hospital in northern India from July 1993 to December 1996. Of these, 88 were transferred to the PICU by the primary physician, 59% were comatose (Glasgow coma score <8), 44% had raised intracranial pressure (ICP), 24% were in shock and 42% had respiratory distress/failure. Seizures occurred during their illness in 64 children, 34 of whom had refractory status epilepticus. Endotracheal intubation was needed in 29 and ventilatory support in 19 children. Most of the life support measures were required during the initial 48 hours. Nineteen (22%) children died, 16 of whom were comatose on admission. Multiple system involvement was associated with higher mortality. There were no deaths among the children who were not transferred to the PICU. Children with ABM who have a Glasgow coma score <8, clinical signs of raised ICP, refractory status epilepticus, shock and/or respiratory compromise should be prioritised to receive PIC.
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