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Updated: Aug 12, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Obstructive sleep apnea syndrome and hypothyroidism (a report of three cases)]
Guangfeng Jiang1, Na Li, Yan Sun
1Department of Otolaryngology, Affiliated Hospital of Medical College Qingdao University, Qingdao, 266003, China.
Objective:
To explore the relationship between obstructive sleep apnea syndrome (OSAS) and hypothyroidism, and to discuss the management experience.
Method:
Three cases of severity OSAS with hypothyroidism were reported and relevant literatures were reviewed. One patient underwent continuous positive airway pressure (CPAP), one patient was performed uvulopalatopharyngoplasty(UPPP), and one case is in follow-up now.
Result:
Thyroxine replacement therapy was effective in improving symptoms and nocturnal sleep apnea.
Conclusion:
Hypothyroidism probably plays a significant role in the pathogenesis of obstructive sleep apnea, the satisfactory results would be obtained by thyroxine replacement therapy, CPAP or surgical treatment can be used as adjuvant therapy in patients with this disease.
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