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Poly-L-lactic acid: a temporary filler for soft tissue augmentation
Birgit Woerle1, C William Hanke, Gerhard Sattler
1Rosenparkklinic--Clinic for Cosmetic Dermatologic Surgery and Plastic Surgery, Darmstadt, Germany.
Journal of Drugs in Dermatology : JDD
|August 12, 2004
Summary
Poly-L-lactic acid is an effective, long-lasting dermal filler for facial wrinkles and lipoatrophy. This synthetic option offers results comparable to fat grafting without surgical harvesting.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Biomaterials Science
Background:
- Poly-L-lactic acid (PLLA) has been available in Europe for soft tissue augmentation since 1999.
- It is a synthetic, resorbable filler used for correcting wrinkles and facial lipoatrophy.
Observation:
- The study reports on the experience with PLLA in 300 patients since 1999.
- PLLA is particularly effective for the lower half of the face.
- Results are excellent and long-lasting, with side effects being technique-dependent.
Findings:
- Poly-L-lactic acid provides excellent and durable aesthetic results for facial soft tissue augmentation.
- Its efficacy is comparable to autologous fat grafting.
- Treatment is suitable for a broader patient population, including the elderly and those with infectious diseases.
Implications:
- PLLA offers a viable alternative to autologous fat grafting, eliminating the need for surgical fat harvesting.
- It expands treatment options for facial rejuvenation and volume correction.
- The technique-dependent nature of results highlights the importance of proper administration.