Identification of a novel HLA-DRB1*12 allele (DRB1*1210) in the Korean population
1National Genome Research Institute, National Institute of Health, Eunpyung-gu, Seoul, South Korea.
Tissue Antigens
|September 14, 2004
Abstract:
At least 11 HLA-DRB1*12 alleles have been identified to date. We report a new HLA-DRB1*12 allele, DRB1*1210, that was identified in the Korean population. This new allele differs from HLA-DRB1*120101 by a single nucleotide at position 40 (G-->A) in exon 1 that falls within codon--16 (GTT-->ATT). This change results in a single valine to isoleucine amino acid alteration.
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