Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary congenital glaucoma: 2004 update.

Ching Lin Ho1, David S Walton

  • 1Singapore National Eye Centre, Singapore, Republic of Singapore.

Journal of Pediatric Ophthalmology and Strabismus
|October 14, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AI to Identify Strain-Sensitive Regions of the Optic Nerve Head Linked to Functional Loss in Glaucoma.

Investigative ophthalmology & visual science·2026
Same author

Glaucoma Management in Sturge-Weber Syndrome Using the Delphi Process.

Ophthalmology. Glaucoma·2025
Same author

GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology.

Nature communications·2025
Same author

Functionally deficient UBOX5 variants and primary angle-closure glaucoma.

Nature communications·2025
Same author

AAV-IKV mediated expression of decorin inhibits EMT and fibrosis in a murine model of Glaucoma and AAV-IKV transduction in Non-Human Primates.

Scientific reports·2025
Same author

Characteristics of Eyes With Asymptomatic Primary Angle Closure Glaucoma With Varying Severity of Visual Field Loss at Presentation.

Journal of glaucoma·2025
Same journal

TeleROP-NI: Modernizing Retinopathy of Prematurity Screening in Northern Ireland to Enhance Decision-making and Ensure Sustainability.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Ocular Microstructural Alterations in Children With Spina Bifida: An Optical Coherence Tomography Study.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Systemic Inflammatory Markers and Their Relationship With Optic Nerve Head Alterations in Pediatric Idiopathic Intracranial Hypertension.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Evaluating Large Language Models to Improve Spanish Patient Education on Childhood Glaucoma.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Comparative Evaluation of Unilateral Recession-Plication Versus Bilateral Three-Muscle Surgery for Large-Angle Exotropia.

Journal of pediatric ophthalmology and strabismus·2026
Same journal

Long-term Visual Sequelae of Shaken Baby Syndrome: A Retrospective Study of 52 Cases.

Journal of pediatric ophthalmology and strabismus·2026
See all related articles

Primary congenital glaucoma is a leading cause of childhood blindness. Early diagnosis and tailored surgical treatment, often goniosurgery, are crucial for managing this condition in pediatric patients.

Area of Science:

  • Ophthalmology
  • Genetics
  • Pediatric Medicine

Background:

  • Primary congenital glaucoma (PCG) is the most common childhood glaucoma, posing a significant threat to vision.
  • Understanding PCG is vital for early intervention and preventing blindness in children.

Purpose of the Study:

  • To clarify the nomenclature, epidemiology, and genetic basis of PCG.
  • To outline diagnostic criteria and effective treatment strategies for PCG.

Main Methods:

  • Review of 287 patients with PCG and analysis of current published data.
  • Examination of epidemiological, genetic, and histopathological findings in PCG.

Main Results:

  • Established consistent nomenclature for PCG, noting variable worldwide incidence.

Related Experiment Videos

  • Identified autosomal recessive transmission, identified CYP1B1 gene mutations, and described trabecular meshwork anomalies.
  • Corneal signs and symptoms are key indicators for diagnosing PCG in children.

    • Conclusions:

    • Thorough examinations are essential to differentiate PCG from other childhood glaucomas and guide treatment.
    • Medical management should be individualized for pediatric patients.
    • Goniosurgery is the primary surgical choice, with alternative procedures available if needed, emphasizing ongoing physician progress.