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Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
Performance measurements of a depth-encoding PET detector module based on position-sensitive avalanche photodiode
P A Dokhale1, R W Silverman, K S Shah
1Department of Biomedical Engineering, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA.
Physics in Medicine and Biology
|October 29, 2004
Summary
We developed a new positron emission tomography (PET) detector with depth of interaction (DOI) capability. This high-resolution PET detector achieves excellent DOI, energy, and timing resolution for advanced imaging applications.
Area of Science:
- Medical Imaging
- Nuclear Instrumentation
- Particle Detectors
Background:
- Positron Emission Tomography (PET) is a crucial medical imaging technique.
- Improving PET detector performance, particularly resolution and efficiency, is an ongoing research area.
- Depth of Interaction (DOI) capability enhances image quality by reducing parallax errors.
Purpose of the Study:
- To develop and characterize a novel high-resolution, high-efficiency PET detector module with DOI capability.
- To evaluate the DOI, energy, and timing resolutions of the developed detector module.
- To assess the suitability of the detector for small animal and breast imaging.
Main Methods:
- Utilized a lutetium oxyorthosilicate (LSO) scintillator array coupled to position-sensitive avalanche photodiodes (PSAPDs) at both ends.
- Employed a 7x7 matrix of LSO crystals (1x1x20 mm3) connected to 8x8 mm2 PSAPDs.
- Measured DOI resolution using the ratio of signal amplitudes from dual-ended PSAPDs; energy resolution by summing signals; timing resolution using coincidence detection.
Main Results:
- Achieved a DOI resolution of 3-4 mm FWHM, consistent across crystal positions and interaction depths.
- Obtained an average energy resolution of 14% FWHM, largely independent of DOI.
- Measured a coincidence timing resolution of 4.5 ns FWHM using a pair of detector modules.
Conclusions:
- The developed PET detector module demonstrates excellent DOI, energy, and timing resolution.
- Performance metrics align with design goals for compact, high-resolution, and high-efficiency PET systems.
- The detector is well-suited for demanding applications like small animal and breast imaging.

