Related Experiment Video
Updated: Aug 17, 2026

Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Published on: June 2, 2023
[Clinical study on modified transpalatine radical operation for carcinoma of nasopharynx]
Yongfeng Si1, Zheng Zhang, Shiqiang Chen
1Department of Otolaryngology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021.
Objective:
To evaluate the method of transpalatine surgical treatment of carcinoma of nasopharynx (NPC).
Method:
The artery palatine major was protected and the resection domain of primary lesion of NPC was expanded by modified hard palatine incision. Preventive radiotherapy and routine chemotherapy was given after the operation.
Result:
Twelve patients were in our report, five of II stage and seven of III stage. In all cases, the incisions in hard palatine were healing by first intention after the operations. The patients were followed up for six months to five years. None case was found relapse or palatal fistula. They all can swallow and speech as normal. Sequelae of radiotherapy was not found.
Conclusion:
Without affecting the healing of the incision, expanding the resective domain of primary lesion of NPC is possible by modified hard palatine incision, and the occurrence of sequelae of radiotherapy can be reduced by giving preventive radiotherapy.

