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[The therapeutic effects of basic fibroblast growth factor injected into tympanic cavity on sensorineural deafness]
Zhijian Zhang1, Yijuan Liu, Yi Dou
1Research Center of Basic and Clinic Medicine of Jiangsu University, Zhenjiang 212001.
Objective:
To evaluate the therapeutic effects of basic fibroblast factor (bFGF) ototopically injected into tympanic cavity on sensorineural deafness.
Method:
40 cases (50 ears) suffering from sensorineural deafness have been treated with bFGF,which was injected into tympanic cavity from 1998 to 1999. The hearing threshold of post-therapy was compaired with that of pre-therapy.
Result:
The total therapeutic effective rate of bFGF on the deafness was 96%. The hearing threshold of post-therapy was much lower than that of pre-therapy in average.
Conclusion:
The bFGF could improve the hearing of sensorineural deafness patients. The method of ototopically injecting bFGF to tympanic cavity was safe and applicable.
