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Updated: Aug 15, 2026
Dissection of the Auditory Bulla in Postnatal Mice: Isolation of the Middle Ear Bones and Histological Analysis
Published on: January 4, 2017
[Clinical study of congenital middle ear malformations]
1Department of Otolaryngology, Peking Union Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100730, China.
Objective:
To search into the diagnosis and treatment of congenital malformation of middle ear.
Method:
Nine patients were involved in our study, exploratory tympanotomy was undergone in all patients (eleven ears) and eight ears were reconstructed the ossicular chain.
Result:
Exploratory tympanotomy showed a variety of abnomalities of the middle ear which were difficult to identify preoperatively, despite the modern imaging techniques. Stapedectomy using a wire prosthesis with an oval window tissue graft to prevent a perilymphatic leak was carried out in four ears, fenestration of vestibule with stapes prosthesis in two ears, removing the fibrotic strand around the incudostapedial joint in one ear, TORP (Total replacement prosthesis) were used in one ear, gain in hearing thresholds was obtained without severe complications occurrence.
Conclusion:
Exploratory tympanotomy is essential to identify congenital conductive hearing loss and wire prosthesis may provide a potential way for reconstruction of ossicular chain.
