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Updated: Aug 14, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[T cell immunity analysis in children with obstructive sleep apnea syndrome]
Hongxia Lu1, Xianliang Fan, Huilan Ren
1The Institute of Otolaryngology of Shandong University, Jinan, 250012, China.
Objective:
To probe into the possible impact on T cell immunity in children with obstructive sleep apnea syndrome (OSAS).
Method:
Lymphocytes in peripheral blood vessel of children with OSAS vs normal controls were checked by APAAP method and analyzed statistically.
Result:
The comparison with the controls showed that CD3+ had no significant difference (P>0.05), CD4+, CD4+/CD8+ were significantly lower, CD8+ was significantly higher in children with OSAS (P<0.01), and the analysis of the LSaO2 and period of history showed that the lower the LSaO2, and the longer the period of history, the more effect to CD4+, CD8+, CD3+/CD8+ (P<0.05).
Conclusion:
T cell immunity are impaired in children with OSAS.

