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[Malacoplakia in the ureter and bladder].
Mikio Koroku1, Hitoshi Tanda, Shuji Katoh
1Department of Sanjyukai Hospital.
Hinyokika Kiyo. Acta Urologica Japonica
|April 28, 2005
Summary
This case study details malacoplakia, a rare condition, found in a patient's ureter and bladder. Treatment led to the disappearance of lesions without long-term complications.
Area of Science:
- Urology
- Pathology
Background:
- Malacoplakia is a rare acquired condition characterized by the presence of Michaelis-Gutmann bodies.
- It typically affects the urinary tract, particularly the bladder, but can involve other organs.
Observation:
- A 78-year-old female presented with hydronephrosis, leading to cystoscopic detection of a yellowish-white lesion at the right ureteral orifice.
- Further examination revealed similar protruding lesions in the right ureter.
- Biopsy confirmed the presence of Michaelis-Gutmann bodies, establishing a diagnosis of malacoplakia.
Findings:
- Transurethral resection was performed, followed by administration of ascorbic acid and bethanechol chloride.
- Post-operative endoscopy at three months showed complete resolution of the bladder and ureteral lesions.
- No ureteral narrowing or vesicoureteral reflux was observed.
Implications:
- This case highlights the successful management of ureteral and bladder malacoplakia with a combination of surgical resection and medical therapy.
- The findings suggest that ascorbic acid and bethanechol chloride may be effective in treating malacoplakia.
- Prompt diagnosis and treatment can prevent long-term sequelae such as ureteral strictures or reflux.